I think this is mainly to do with tribalism, which is a very very ancient set of instincts (we share them to a large degree with the other apes, just look at how chimp tribes behave towards each other). People are built to fit themselves into kin groups, which works pretty well when you're talking about relative small societies of a hundred or a few thousand individuals. Essentially it is an "us vs. them", "friend vs. stranger" recognition system.
If someone is seen as a stranger, they are a potential threat, and actions can be taken against them that one would not take against a member of one's own kin group or society (this is why murder of a relative or close friend is still seen in most societies as a much higher crime than murder of a stranger or an acquaintance). Through the ages demagogues have been able to manipulate this basic tribal instinct to group people based upon relationship to further all sorts of atrocities. Whether it's persecution, exile, slavery or genocide, once you've convinced a populace that your desired target group is somehow alien, you can convince that populace to do almost anything.
It's as the old story goes (and time for the Godwin); Hitler convinced an entire nation made of up people who adhered to a religion whose basic tenet was "love thy brother" that persecution and ultimately murder of millions of members of ethnic groups (Jews and Roma in particular) was perfectly fine, and yet even Hitler was a vegetarian who loved his dogs.
Whether this "empathy switch" in psychopaths is related to that I don't know. Obviously even in normal people there is a way to trigger the dehumanizing of groups if they can be convinced that they are alien threats. Mind you even look like genocides like the Jewish Holocaust or the Rwandan genocide, there was long standing prejudice and mistrust against the targeted group, so it's not as if appeared out of nowhere.
Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/wa9AUve1H00/story01.htm
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